哈佛大学刘小乐教授讲授的计算生物学和生物信息学导论 (2020 视频+资料）-技术圈

生物信息学习的正确姿势

NGS系列文章包括NGS基础、高颜值在线绘图和分析、转录组分析（Nature重磅综述|关于RNA-seq你想知道的全在这）、ChIP-seq分析（ChIP-seq基本分析流程）、单细胞测序分析 (重磅综述：三万字长文读懂单细胞RNA测序分析的最佳实践教程)、DNA甲基化分析、重测序分析、GEO数据挖掘（典型医学设计实验GEO数据分析 (step-by-step)）、批次效应处理等内容。

该课程由哈佛大学刘小乐教授教授，内容涵盖生物信息和高通量测序的很多方面，基本生信、转录组、表观组、突变组、三维结构和单细胞等领域，是不可多得的生信学习视频和文字教程，推荐给各位朋友。

课程网站：https://liulab-dfci.github.io/teaching (正在申请授权，欢迎志同道合的朋友一起加入给视频添加中文字幕)

课程目录

2020 STAT115 Lect 1-1 Bioinfo History
2020 STAT115 Lect 1-2 Big Data Challenge
2020 STAT115 Lect 1-3 Bioinfo vs Comp Bio
2020 STAT115 Lect 1-4 Course Info
2020 STAT115 Lect 2-1 Three Generations of Sequencing
2020 STAT115 Lect 2-2 FASTQ and FASTQC
2020 STAT115 Lect 2-3 BLAST and Suffix Arrays
2020 STAT115 Lect 2-4 BWT and LF Mapping
2020 STAT115 Lect 2-5 Borrows-Wheeler Alignment
2020 STAT115 Lect 2-6 SAM and BAM files
2020 STAT115 Lect 3-1 RNA-seq Experimental Design
2020 STAT115 Lect 3-2 RNA-seq Alignment and QC
2020 STAT115 Lect 3-3 RNA-seq Quantification
2020 STAT115 Lect 3-4 RNA-seq Read Distribution
2020 STAT115 Lect 4-1 Differential RNA-seq
2020 STAT115 Lect 4-2 Multiple Hypotheses Testing and False Discovery Rate
2020 STAT115 Lect 4-3 Gene Ontology
2020 STAT115 Lect 5-1 Gene Set Enrichment Analyses
2020 STAT115 Lect 5-2 Consensus Clustering
2020 STAT115 Lect 5-3 Hierarchical Clustering
2020 STAT115 Lect 5-4 K-means Clustering
2020 STAT115 Lect 6-1 KNN and MDS
2020 STAT115 Lect 6-2 PCA
2020 STAT115 Lect 6-3 Batch Effect Removal
2020 STAT115 Lect 8-1 scRNA-seq
2020 STAT115 Lect 8-2 Processing and QC scRNA-seq
2020 STAT115 Lect 8-3 Differential Expression in scRNA-seq
2020 STAT115 Lect 9-1 scRNA-seq Batch Effect Removal
2020 STAT115 Lect 9-2 Gene Expression Module Summary
2020 STAT115 Lect 9-3 Gene Expression Analysis Scenario
2020 STAT115 Lect 10-2 Expectation Maximization for Motif Finding
2020 STAT115 Lect 10-3 Gibbs Sampling for Motif Finding
2020 STAT115 Lect 10-4 Motif Finding General Practices
2020 STAT115 Lect 11-1 ChIP-seq
2020 STAT115 Lect 11-1 Transcription Regulation
2020 STAT115 Lect 11-2 MACS and QC for ChIP-seq
2020 STAT115 Lect 11-3 TF Interactions from ChIP-seq
2020 STAT115 Lect 11-4 TF Target Genes from ChIP-seq
2020 STAT115 Lect 12-1 Epigenetics
2020 STAT115 Lect 12-2 DNA Methylation
2020 STAT115 Lect 12-3 DNA Methylation Function
2020 STAT115 Lect 12-4 Nucleosome Positioning
2020 STAT115 Lect 13-1 Histone Modifications
2020 STAT115 Lect 13-2 Histone marks on enhancers
2020 STAT115 Lect 13-3 Histone marks on genes
2020 STAT115 Lect 13-4 DNase-seq
2020 STAT115 Lect 13-5 ATAC-seq
2020 STAT115 Lect 15-1 HiC Introduction
2020 STAT115 Lect 15-2 Topologically Associating Domains
2020 STAT115 Lect 15-3 Chromatin Compartments
2020 STAT115 Lect 15-4 Regulatory Network
2020 STAT115 Lect 16-1 Intro to Single-Cell ATAC-seq
2020 STAT115 Lect 16-2 Preprocessing and QC scATAC-seq
2020 STAT115 Lect 16-3 Analysis of scATAC-seq
2020 STAT115 Lect 16-4 Integrating scATAC-seq with scRNA-seq
2020 STAT115 Lect 17-1 Module II Review
2020 STAT115 Lect 17-2 Module II Practice Scenarios
2020 STAT115 Lect 17-3 SNP and GWAS Intro
2020 STAT115 Lect 17-4 GWAS Artifacts and eQTL
2020 STAT115 Lect 18-1 Intro Functional Annotate GWAS
2020 STAT115 Lect 18-2 GWAS Functional Enrichment
2020 STAT115 Lect 18-3 Find Causal SNPs
2020 STAT115 Lect 18-4 Predict disease risk
2020 STAT115 Lect 19-1 Introduction to Cancer Genome Analysis
2020 STAT115 Lect 19-2 Cancer. Mutation Characterization
2020 STAT115 Lect 19-3 Cancer Mutation Patterns
2020 STAT115 Lect 19-4 Tumor Purity and Clonality
2020 STAT115 Lect 19-5 Interpret Tumor Mutations
2020 STAT115 Lect 19-6 Find Cancer Genes
2020 STAT115 Lect 19-7 Summary and Future
2020 STAT115 Lect 20-1 Tumor Subtypes
2020 STAT115 Lect 20-2 Survival Analysis
2020 STAT115 Lect 20-3 Oncogenes and Tumor Suppressor Mutations
2020 STAT115 Lect 20-3 scRNA-seq Clustering and Visualization
2020 STAT115 Lect 20-4 Cancer Epigenetics
2020 STAT115 Lect 20-5 Cancer Hallmarks
2020 STAT115 Lect 22-3 Tumor Immune Deconvolution
2020 STAT115 Lect 22-4 Immune Receptor Repertoires
2020 STAT115 Lect 23-1 Immune Signaling
2020 STAT115 Lect 23-2 Immunotherapy Biomarkers
2020 STAT115 Lect 23-3 CRISPR Screens
2020 STAT115 HaploReg
2020 STAT115 GWAS catalogue
2020 STAT115 LD Link
2020 STAT115 OpenCRAVAT Demo

视频地址：https://www.youtube.com/watch?v=UNAUcAojgh4&list=PLeB-Dlq-v6tY3QLdQBA7rwb4a7fK9mLpv&index=3 (点击阅读原文直达)。

正在申请授权，欢迎志同道合的朋友一起加入给视频添加中文字幕。